This paper reviews preclinical and clinical data on available cyanide antidotes and considers the profiles of these antidotes relative to properties of a hypothetical ideal cyanide antidote. Critical assessment of cyanide antidotes is needed to aid in therapeutic and administrative decisions that will improve care for victims of cyanide poisoning (particularly poisoning from enclosed-space fire-smoke inhalation), and enhance readiness for cyanide toxic terrorism and other mass-casualty incidents. The international medical community lacks consensus about the antidote or antidotes with the best risk-benefit ratio. ' Facts about Cyanide.' Centers for Disease Control and Prevention, 2018.Cyanide has several antidotes, with differing mechanisms of action and diverse toxicological, clinical, and risk-benefit profiles. ' Cyanides in the environment-analysis-problems and challenges.' Environmental Science and Pollution Research, vol. Jaszczak Ewa, Zaneta Polkowska, Sylwia Narkowicz, and Jacek Namiesnik. ' Sodium Cyanide: Systematic Agent.' The National Institute for Occupational Safety and Health (NIOSH), 2011. ' Cyanide Toxicity.' NCBI StatPearls, National Center for Biotechnology Information, 2019.

' Challenges in the diagnosis of acute cyanide poisoning.' Clinical Toxicology (Phila), vol. ' Acute cyanide poisoning among jewelry and textile industry workers.' American Journal of Emergency Medicine, vol. ' Metabolism of cyanogenic glycosides: A review.' Food and Chemical Toxicology, vol. Bortey-Sam, Nesta, et al. ' Diagnosis of cyanide poisoning using an automated, field-portable sensor for rapid analysis of blood cyanide concentrations.' Analytica Chimica Acta, vol.

Cyanide antidote kit